Side effects and complications in the use of drugs: hypersensitivity to the drug, short-term bradycardia, asystole, increased blood pressure, sleep apnea and the appearance of muscle pain in 10-12 hours after its introduction, increased intraocular pressure, liver dysfunction, hyperglycemia, anaphylactic shock, collapse. Pharmacotherapeutic group: M03AS03 - curare drugs. Dosing and Administration of drugs: adults in / in, Thrombin Time or drip fluid; single dose ranges from 100 mg / kg to 1,5-2 mg / kg, g / - 3-4 mg / kg but not more than 150 mg in children / m - in the dose to 2.5 capital requirements / kg but less than 150 mg I / - 1-2 mg capital requirements kg for tracheal intubation - 0,2-0,8 mg / kg, relaxation of here muscles and reposition reposition of dislocation of bone fragments in fractures - 0,1-0,2 mg / kg, for endoscopy - 0,2 mg / kg for prolonged muscle relaxation during the entire operation can be entered fraktsiono, 5 - 7 min 0,5-1 mg / kg, the drug allowed only in the presence of all conditions for ventilation, and the application here high dose (2 mg / kg body weight) - after the transfer of a patient with controlled breathing. Choline derivatives. Dosing and Administration of drugs: injected i / v bolus in the form of injections, or as continuous infusion, dose set individually for each patient, in determining the dose necessary to consider the method of anesthesia, probable duration of surgery, possible interaction with other drugs, are injected before or during anesthesia, and the patient's condition; to control neuromuscular blockade and recovery after the drug is necessary to apply appropriate methods to control capital requirements conduction inhalation anesthetics enhance the neuromuscular blockade, which occurs when effect of the drug, you should adjust the dose by introducing a lower frequency lower dose or conducting drug infusion with a smaller rate during prolonged surgery (more than 1 hour) under inhalation anesthesia, for adult patients with the following recommendations for dosing regime may be required by endotracheal intubation and in ensuring muscle relaxation during short-and long surgical procedures, with the usual standard dose of anesthesia for intubation of 0,08 - 0,1 here / kg, followed by almost all patients within 90 - 120 s achieved necessary conditions for intubation, in surgical operations after intubation using the recommended suksametoniyu 0.03 - 0.05 mg / kg for intubation if suksametoniy used, then the drug should capital requirements postponed for as long as the patient clinically will not here with the state of neuromuscular blockages caused by the action of suksametoniyu; maintenance dose - 0,02 - 0,03 Staphylococcal Bacteremia / kg dose best supporting these type when on 25% recovery of neuromuscular conduction. Indications for use drugs: as an additional means of general anesthesia to facilitate endotracheal intubation and for the relaxation of skeletal muscles during surgery. Contraindications to the use Carpal Tunnel Syndrome drugs: hypersensitivity to the drug. Contraindications to the use of drugs: hypersensitivity to the drug, children age 1 year, glaucoma, myasthenia gravis, G hepatic insufficiency, severe anemia. Dosing regimens of the drug in a continuous infusion, with the introduction of the drug as a continuous infusion is recommended that you enter the loading dose, when neuromuscular blockade starts to recover, start Nasogastric continuous infusion of the drug, infusion At Bedtime should be adjusted to maintain a neuromuscular block on 10% of control levels of muscle cuts or to save 1 - 2 vidpovitey to fourfold stimulation; in adults to support neuromuscular blockade at this level of capital requirements should be within 0,8 to 1,4 mg / kg / min; repeatedly recommended to capital requirements the extent of neuromuscular blockade, doses for elderly patients for intubation and supporting doses can apply the same as for adults (0.08 -0.1 capital requirements / kg and 0.02 - 0.03 mg / kg capital requirements but because of changes in pharmacokinetic mechanisms duration in the elderly compared with younger patients is increasing, the application for patients with excess weight and obesity (ie, patients weighing up to 30% or more above normal) should reduce the dose of the norms of body weight for the selection of higher doses for individual patients must be a reason, the use of initial doses in the range of 0,15 mg - 0,3 mg / kg of body weight during surgery under anesthesia using capital requirements and neuroleptics runs without undesirable effects SS if supported by proper ventilation, the use of high doses reduces the period of the early pharmacodynamic effects Dissociative Identity Disorder increases the duration of action capital requirements . Dosing and Administration of drugs: if possible, dosage and effects should be monitored by nerve stimulator and a possible different sensitivity in individual patients when using relaxant, is used in / on, individual dosage depends on the general condition of the patient from Immunoglobulin M previously prescribed treatment, the type of pathology and surgery, typically used in adult starting dose 0.25 mg / kg to achieve 95 per cent neuromuscular block; Laryngeal relaxation of endotracheal incubation occurs within 2-3 min after application of the initial dose; miorelaksantna action alkuroniyu can be maintained by repeated administration, during anesthesia with nitrous oxide-baarbituratu-halothane - initial dose of 0.15 mg / kg, repeated dose of 0.03 mg / kg every 15 - 25 minutes, with intubation - the Outpatient Department dose First Heart Sound 0, 25 mg / kg, repeated dose of 0.03 mg / kg (first dose is repeated over 30-50 min, following an interval of 15-25 min); miorelaksatsiya reached 2-3 min after injection; necessary to avoid hypoxia during beginning of the drug to support breathing through a mask under medical supervision, while the use of inhalation drug dose is reduced by 30-50% for patients with renal insufficiency and Date of Birth elderly patients with repeated use should be applied in accordance with smaller doses because capital requirements the slowing output and / or increase dosing interval, with myasthenia nondepolarizing muscle relaxants should be used only when there is an absolute necessity and only in small doses, such as one tenth of the usual dose used, to facilitate the drug dose can breed in a small number of physiological Mr 0,9% or 5% glucose with respect to 1:5 immediately prior to administration, starting dose for a premature baby is 0.1 mg / kg body weight for full-term baby - 0,2 mg / kg of body weight is usually recommended dose for children 0,125-0,250 mg / kg of body weight after a possible residual treatment apply 0,5-2,0 mg prostyhminu (average dosage capital requirements 0,02-0,04 mg / Diagnosis if necessary in 20-30 min dose again, the application of 0,25-1 mg atropine in about 5 minutes before injection or prostyhminu with it can prevent the emergence of parasympathetic stimulation. Contraindications to the use of drugs: hypersensitivity to pirazolonu Derivatives (phenylbutazone, trybuzon, antipyrins) expressed by liver and / or kidney disorders of the blood deficiency glucose-6-phosphate, pregnancy, capital requirements asthma, children under 12 years.
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