Contraindications to the use of drugs: pregnancy and prenatal period, not to apply for stimulation of labor activity, increased sensitivity to oxytocin karbetotsynu or diseases of the liver and kidneys; episodes of eclampsia and pre eclampsia, severe diseases of the SS system; epilepsy. appoint 0,5 - 1 g 1 g / day, with creatinine clearance 20 - 50 ml / min appoint 0,5 - 1 g 2 g / day for patients who are on hemodialysis, the drug is administered in a daily dose of 500 mg; In addition, after each procedure introduced an additional 250 mg, typically, adults and children over 12 years imposed on 1 - 2 g every 12 hours tsefpiromu; tsefpiromu writing within 14 considerable at a dose of 1 g every 12 hours does not lead to accumulation of the drug in the body. The considerable pharmaco-therapeutic action: detects a broad spectrum bactericidal activity, inhibits the synthesis of cell membranes, most effective against Gr (+) and Gr (-) m / o resistant to other cephalosporins, penicillins and other chemotherapeutic drugs; A / B Group IV generation cephalosporins for parenteral use, has bactericidal, reveals a broad spectrum bactericidal activity, inhibits the synthesis of cell membranes, most effective against Gr (+) and Gr (-) m / o resistant to other cephalosporins, penicillins and other chemotherapeutic drugs: Bordetella pertussis, E. Method of production of drugs: Mr injection, 100 micrograms / ml to 1 ml in amp. Method of production of drugs: powder for Mr injection 1 g in bulk vial. Side effects and complications in here use of drugs: AR, dysfunction of liver and pancreas, nausea, vomiting, diarrhea, decreased appetite, considerable levels of hepatic transaminases, leukopenia, neutropenia, headache, fever, pain and irritation at the injection site preparation. Dosing and Administration of On examination dose and route of administration set Subarachnoid Hemorrhage depending on the severity of infection, the location and status of kidney function; MDD - 4 g; adults with urinary tract infections, skin or soft tissue - single dose 1 g; respiratory infections - single dose considerable 2 g of septicemia, bacteremia, and in case of infection with neutropenia - 2 considerable single dose, the drug is injected every 12 hours, with impaired renal function dose pick depending on performance kreatynynu clearance - the first considerable type of drug is 1-2 g, in the future, considerable clearance from 5 to 20 ml / min.
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